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교수 및 교실소개

은혁수 프로필 사진
이름
은혁수   이메일아이콘
전공
내과학
연락처
연구실
교수연구동 1층 1001호

최종학력

2001.3-2003.2 충남대학교
2003.3-2007.2 충남대학교
2009.3-2011.2 충남대학교
2012.2-2016.2 한국과학기술원 (KAIST)

경력

2007.3-2008.2 충남대학교병원 [수련의 ]
2008.3-2012.2 충남대학교병원 내과 [전공의]
2012.2-2016.2 한국과학기술원 의과학연구센터 [전문연구요원 ]
2016.3-2018.2 충남대학교병원 [소화기내과 전임의사 ]
2018.3-현재 충남대학교 의과대학 [내과학교실 소화기내과 기금조교수 ]

관심연구분야

- 간염(급만성간염, 지방간, 알코올성 간질환, 자가면역질환)

- 간경변증

- 간암

논문

1. Kang SH, Kim JS, Joo JS, EunHS, Lee ES, Moon HS, Kim SH, Sung JK, Lee BS, Jeong HY, Kim Y, Sohn MK, Jee S. Efficacy of Early Endoscopic Intervention for Restoring Normal Swallowing Function in Patients with Lateral Medullary Infarction. Toxins (Basel). 2019 Mar 4;11(3)

2. Kim S, EunHS, Jo EK. Roles of Autophagy-Related Genes in the Pathogenesis of Inflammatory Bowel Disease. Cells. 2019 Jan 21;8(1)

3. Choi WM, EunHS, Lee YS, Kim SJ, Kim MH, Lee JH, Shim YR, Kim HH, Kim YE, Yi HS, Jeong WI. Experimental Applications of in situ Liver Perfusion Machinery for the Study of Liver Disease. Mol Cells. 2019 Jan 31;42(1):45-55

4. Cho SY, Kim S, Son MJ, Rou WS, Kim SH, EunHS*, Lee BS*. Clinical Significance of the Thioredoxin System and Thioredoxin-Domain-Containing Protein Family in Hepatocellular Carcinoma. Dig Dis Sci. 2018 Oct 4. (*: Co-corresponding author)

5. Eun HS*, Cho SY*, Lee BS, Seong IO, Kim KH. Profiling cytochrome P450 family 4 gene expression in human hepatocellular carcinoma. Mol Med Rep. 2018 Oct 1. (*: Co-First author)

6. Yun GY, EunHS, Kim JS, Joo JS, Kang SH, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY. Colonoscopic withdrawal time and adenoma detection in the right colon. Medicine (Baltimore). 2018 Aug;97(35):e12113.

7. Eun HS*, Cho SY*, Lee BS, Kim S, Song IS, Chun K, Oh CH, Yeo MK, Kim SH, Kim KH. Cytochrome P450 4A11 expression in tumor cells is a favorable prognostic factor for hepatocellular carcinoma patients. J Gastroenterol Hepatol. 2018 Aug 2. [Epub ahead of print]. (*: Co-First author)

8. Cho SY, Kim JS, EunHS, Kang SH, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY, Moon HS. Expression of NOX family Genes and Their Clinical Significance in Colorectal Cancer. Dig Dis Sci. 2018. May 21. [Epub ahead of print]

9. Park DH, Yun GY, EunHS, Joo JS, Kim JS, Kang SH, Moon HS, Lee ES, Lee BS, Kim KH, Kim SH. Fimasartan-induced liver injury in a patient with no adverse reactions on other types of angiotensin II receptor blockers: A case report. Medicine (Baltimore). 2017 Nov;96(47):e8905.

10. Kim SY, Jeong JM, Kim SJ, Seo W, Kim MH, Choi WM, Yoo W, Lee JH, Shim YR, Yi HS, Lee YS, EunHS, Lee BS, Chun K, Kang SJ, Kim SC, Gao B, Kunos G, Kim HM, Jeong WI. Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex. Nat Commun. 2017. Dec 21;8(1):2247

11. Eun HS*, Cho SY*, Joo JS, Kang SH, Moon HS, Lee ES, Kim SH, Lee BS. Gene expression of NOX family members and their clinical significance in hepatocellular carcinoma. Sci Rep. 2017. Sep 11;7(1):11060 (*: Co-First author)

12. Eun HS, Lee BS, Kwon IS, Yun GY, Lee ES, Joo JS, Sung JK, Moon HS, Kang SH, Kim JS, Shin HJ, Kim TK, Chun KS, Kim SH. Advantages of laparoscopic radiofrequency ablation over percutaneous radiofrequency ablation in hepatocellular carcinoma. Dig Dis Sci. 2017. 62:2586-2600 (First author)

13. Moon HS, Yun GY, Kim JS, EunHS, Kang SH, Sung JK, Jeong HY, Song KS. Risk factors for metachronous gastric carcinoma development after endoscopic resection of gastric dysplasia: Retrospective, single-center study. World J Gastroenterol. 2017 Jun 28;23(24):4407-4415.

14. Kim TK, Kang SH, Moon HS, Sung JK, Jeong HY, EunHS. Pulmonary sarcoidosis that developed during the treatment of a patient with Crohn disease by using infliximab. Ann Coloproctol. 2017 Apr;33(2):74-7.

15. Park SH, Seo WH, EunHS, Kim SY, Jo E, Kim MH, Choi WM, Lee JH, Shim YR, Cui CH, Kim SC, Hwang CY, Jeong WI. Protective effects of ginsenoside F2 on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation in mice. Biochem Biophys Res Commun. 2016, Sep, 30;478(4):1713-9.

16. Lee YS, EunHS, Kim SY, Jeong JM, Seo W, Byun JS, Jeong WI, Yi HS. Hepatic immunotyping for streptozotocin-induced hyperglycemia in mice. Sci Rep. 2016, July 28;6:30656.

17. Seo W, Eun HS, Kim SY, Yi HS, Lee YS, Park SH, Jang MJ, Kim SC, Han YM, Park KG, Jeong WI. Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis. Hepatology. 2016 Aug;64(2):616-31.

18. Eun HS, Jeong WI. Dual notch signaling in proinflammatory macrophage activation. Hepatology. 2016, Apr;63(4):1381-3 (First author)

19. Lee YS, Yi HS, Suh YG, Byun JS, EunHS, Kim SY, Seo W, Jeong JM, Choi WM, Kim MH, Kim JH, Jeong WI. Blockade of Retinol Metabolism Protects T cell-induced Hepatitis by Increasing Migration of Regulatory T Cells. Mol Cells. 2015 Nov 30; 38 (11):998-1006.

20. Yi HS*, EunHS*, Lee YS, Jung JY, Park SH, Park KG, Choi HS, Suh JM, Jeong WI. Treatment with 4-methylpyrazole modulated stellate cells and natural killer cells and ameliorated liver fibrosis in mice. Plos One. 2015, 10(5):e0127946 (* : Co-first author)

21. Suh YG, Kim JK, Byun JS, Yi HS, Lee YS, EunHS, Kim SY, Han KH, Gregg Deuster, Scott L. Friedman, and Jeong WI. CD11b+Gr1+bonemarrowcellsameliorateliverfibrosisbyproducinginterleukin-10inmice.Hepatology, 2012, 56(5):1902-12

22. Goh PG, Jeong HY, Kim MJ, EunHS, Kim HJ, Kim ES, Kim YJ, Lee SY, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS. Clinical outcomes of endoscopic submucosal dissection for undifferentiated or submucosal invasive early gastric cancer. Clin Endosc, 2011 Dec;44(2):116-22.

23. Eun HS, Kim MJ, Kim HJ, Ko KH, Moon HS, Lee ES, Kim SH, Lee HY, Lee BS. The retrospective cohort study for survival rate in patients with advanced hepatocellular carcinoma receiving radiotherapy or palliative care. Korean J Hepatol. 2011 Sep;17(3):189-98. (First author)

24. Goh PG, Kim MJ, Kim HJ, EunHS, Kim ES, Kim YJ, Lee SY, Moon HS, Lee ES, Kim SH, Lee BS, Lee HY. Importance of medication adherence

특허

1. Patent of Korea, Patent number, 10-1643555, Title: Selection method of functionally matured human embryonic stem cell-derived hepatocytes using STRA6 marker (Patent registration completed)

2. Patent of Korea, Patent number, 10-1646565, Title: Method for improving drug metabolic function of human embryonic stem cell-derived hepatocytes using retinoic acids (Patent registration completed)

3. Patent of Korea, Patent number, 10-1694315, Title: Method for improving drug metabolic function of human embryonic stem cell-derived hepatocytes using hepatic stellate cells (Patent registration completed)

수상경력

- 2014.11
Korea Yakult Yoon Deok Byung Foundation Scholarship

- 2015.1
Excellent poster award in the Korean Society for Cell Biology (KSCB)

- 2017.10
International Young Investigator Travel Award Presented in honor of Professor C. Y. Kim (Chung Yong Kim) from AASLD 2017

연구실소개

충남대학교병원 의생명연구센터 소화기내과 간질환연구실2 (Lab of Liver Research 2)